Screening of traditionally used plants for in vivo antimalarial activity in mice
نویسندگان
چکیده
منابع مشابه
Screening of traditionally used plants for in vivo antimalarial activity in mice.
Aqueous ethanol (80%) extracts of six plants used traditionally for treatment of malaria, Vepris glomerata (F.Hoffm.) Engl (Rutaceae), Maranthus floribunda (Bak.) F.White (Chrysobalanaceae), Strophanthus eminii Asch. & Pax ex Pax (Apocynaceae), Cassia abbreviata Oliv. (Leguminosae) and Caesalpinia bonducella L. Fleming (Fabaceae) were screened for antimalarial activity to establish validity of ...
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Developing countries, where malaria is endemic, depend strongly on traditional medicine as a source for inexpensive treatment of this disease. However, scientific data to validate the antimalarial properties of these herbal remedies are scarce. Consequently, it is important that antimalarial medicinal plants are investigated, in order to establish their efficacy and to determine their potential...
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Thirty extracts obtained from 10 endemic plant species belonging to 8 plant families used in the traditional medicine in Socotra have been tested for cytotoxic activity against FL-cells. Extracts of Eureiandra balfourii and Commiphora ornifolia showed the strongest activity against FL-cells with IC(50) < 10 microg/ml and 39.3 microg/ml respectively.
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Ten plant extracts commonly used by the Meru community of Kenya were evaluated for the in vitro antiplasmodial, in vivo antimalarial, cytotoxicity and animal toxicity activities. The water and methanol extracts of Ludwigia erecta and the methanol extracts of Fuerstia africana and Schkuhria pinnata exhibited high antiplasmodial activity (IC(50) < 5 microg/mL) against chloroquine sensitive (D6) a...
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ETHNOPHARMACOLOGICAL RELEVANCE Malaria continues to kill over a million people each year and in many populations affected by malaria, conventional drugs are often unaffordable or inaccessible. Historically, plants have been a prominent source of antimalarial drugs. Those plants currently used by indigenous people to treat malaria should be documented and investigated as potential sources of new...
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ژورنال
عنوان ژورنال: African Journal of Traditional, Complementary and Alternative Medicines
سال: 2010
ISSN: 0189-6016
DOI: 10.4314/ajtcam.v6i2.57088